Relocalizing Transcriptional Kinases to Activate Apoptosis with Roman Sarott and Sai Gourisankar скачать в хорошем качестве

Relocalizing Transcriptional Kinases to Activate Apoptosis with Roman Sarott and Sai Gourisankar

In this Research Spotlight episode, Dr. Roman Sarott and Dr. Sai Gourisankar share their work on relocalizing transcriptional kinases to activate apoptosis. Key reference: Science 386, eadl5361 (2024) https://www.science.org/doi/10.1126/s... Additional references (in order of appearance): Hanahan and Weinberg, Cell 2011 Bishop et al., Trends Pharmac. Sci. 2017 Hatzi et al., Nat Immunol. 2019; Ptashne and Gann, Nature 1997 Phan & Dalla-Favera Nature 2004; Kerres et al. Cell Rep. 2017 Alerasool et al., Mol. Cell 2022; Kolata, G. The New York Times July 31, 2023 For a review on CDK9 inhibitors: Gu et al. J. Med. Chem. 2022; for BCL6 inhibitors: Wu et al. J. Med. Chem. 2020 Hornberger and Araujo, J. Med. Chem. 2023 Alerasool et al., Mol. Cell 2022; Nabet et al., Nat. Chem. Biol. 2018 For the CDK12/13 inhibitor used in CDK-TCIP3, see Yang et al. J. Med. Chem. 2022 Stanton, Chory, and Crabtree Science 2018; Winter, ACS Chem. Biol. 2024