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South Africa has officially approved a new HIV prevention injection you only take twice a year — and it could change everything. Lenacapavir is a long-acting HIV prevention medication (PrEP) shown in two landmark randomized clinical trials (PURPOSE 1 and PURPOSE 2) to have a high efficacy. But what does that actually mean? How does it work? Who can get it? And will it really improve HIV prevention access? With 8.45 million people living with HIV in South Africa, expanding prevention options matters Let me know in the comments: Would you prefer an injection twice a year or daily pills? Do you think easier prevention changes behaviour? Purpose 1: for adolescent girls and young women https://clinicaltrials.gov/study/NCT0... Purpose 2: for MSM, trans and, gender diverse individuals https://clinicaltrials.gov/study/NCT0... TIMESTAMP 00:00 Intro 00:22 Why the daily oral PrEP was not enough? 01:23 What is Lencapavir and how does it work? 03:25 Purpose 1 and Purpose 2 Randomized Controlled Trials (RCT) results explained 05:09 Where and how can you get Lenacapavir injectable PrEP? 06:06 What are the side effects of Lenacapavir injectable PrEP? 06:55 What are the benefits of taking Lenacapavir injection? 08:25 Why does having Lencapavir injectable PrEP matter? 10:01 Bigger picture questions of having a twice-yearly injectable PrEP