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In today's episode we reveal how you can reverse insulin resistance, lower visceral fat, and restore metabolic health by fixing a hidden bottleneck in the body’s detox system — the glycine-glutathione pathway. After struggling with elevated fasting glucose, high HOMA-IR, inflammation, and oxidative stress, Dr. Miles discovered that glycine deficiency was limiting glutathione production, the body’s master antioxidant and primary detox molecule. Low glutathione leads to mitochondrial dysfunction, insulin resistance, toxin accumulation, and chronic inflammation — all major drivers of metabolic disease. By supplementing glycine, increasing bile-binding fiber (psyllium), and combining it with strategic fasting and sauna-induced detoxification, he increased glutathione levels by 43%, reduced oxidative stress, and cut insulin resistance by 68%. This led to dramatic improvements in blood sugar, triglycerides, visceral fat, mitochondrial function, autophagy, and inflammation. This video explains the exact molecular mechanisms behind how detoxification failure disrupts insulin signaling, how glutathione controls mitochondrial health, and why most diets and exercise plans fail to fix the real root cause of metabolic dysfunction. If you’re dealing with prediabetes, insulin resistance, stubborn belly fat, fatigue, brain fog, or slow metabolism, this protocol reveals a scientifically backed way to restore cellular function from the inside out. Dr. Walter Miles Professor of Genetics and Metabolic Biology