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Session 1 of the "Reaching the 95-95-95 targets: How can industry contribute?" workshop. On 9 June 2021, United Nations Member States adopted a political declaration1 calling on countries to provide access to people-centred and effective HIV combination prevention options for 95% of all people vulnerable to acquiring HIV within all epidemiologically relevant groups, age groups and geographic settings. The declaration also calls on countries to ensure that 95% of people living with HIV know their HIV status, 95% of people who know their status are on HIV treatment and 95% of people on HIV treatment are virally suppressed. This declaration reinforces and accelerates the UNAIDS Fast-Track strategy to end the AIDS pandemic by 2030. The strategy, adopted on 18 November 2014, set out the 90-90-90 testing and treatment targets to be achieved by 2020. Globally and at regional level, the 90-90-90 targets were largely missed. However, progress has been steady. At least eight countries in settings as diverse as Botswana and Switzerland achieved the 90-90-90 targets by 2020, showing that with sufficient funding, political will, policies and evidence-informed interventions, the targets were not overly ambitious. Learning from both the success and failures towards reaching the 2020 targets is essential to increase the chance of ending AIDS as a threat to public health by 2030. Success will require commitment from all stakeholders in the HIV response. The Industry Liaison Forum at IAS – the International AIDS Society – held a series of online roundtables to explore important gaps and how the biomedical industry can actively contribute to achieving the 95-95-95 target by 2025.