When Glioblastoma Does Not Look Like Glioblastoma: A Case of Diagnostic Delay скачать в хорошем качестве

When Glioblastoma Does Not Look Like Glioblastoma: A Case of Diagnostic Delay

In this video, a case-based discussion revolves around glioblastoma multiforme (GBM) with an atypical, encephalitis-like presentation, focusing on the diagnostic uncertainty, radiological evolution, and neurosurgical decision-making involved. The case demonstrates how early glioblastoma can deviate from classic imaging patterns, initially resembling inflammatory or infectious pathology, and how serial imaging and clinical progression ultimately guide the diagnosis and management. The discussion is framed from a medical student perspective and covers: • Initial clinical presentation and differential diagnosis • CT and MRI findings and their evolution over time • Radiological features that mimicked encephalitis • Indications for surgery and rationale for open microsurgical resection • Histopathological confirmation of glioblastoma multiforme • Key learning points relevant to neurosurgical and neurological practice All imaging and case details are derived from peer-reviewed, open-access literature. This video is intended solely for educational purposes. All patient information shown was anonymized prior to publication in the original source. This content does not constitute medical advice. References & Sources: 1. Elkholy MM, et al. Multifocal glioblastoma multiforme with encephalitis-like presentation: a case report. Egyptian Journal of Radiology and Nuclear Medicine, 2021. 2. Stupp R, et al. Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma. New England Journal of Medicine, 2005. 3. Sanai N, Berger MS. Extent of resection influences outcomes for patients with gliomas. Neurosurgery, 2008. 4. Louis DN, et al. WHO Classification of Tumours of the Central Nervous System. #glioblastoma #glioblastomamultiforme #GBM #neurosurgery #braintumor #neuro-oncology #atypicaltumor #craniotomy #MRI #CT #ClininicalCase #TemporalLobeGlioma International Agency for Research on Cancer, 2016 / 2021 update.