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Vote for Open Neuroimaging Laboratory for the Open Science Prize here! http://bit.ly/openneurolab The Open Neuroimaging Laboratory (http://openneu.ro/start/) is a project to facilitate finding, improving, and reusing the massive amount of brain MRI data available online. This data represents an enormous funding effort and the work and goodwill of thousands of participants. BrainBox, our first application, transforms these static MRIs into “living” matter for collaborative curation and analysis using only a Web browser. Users can work, discuss, edit and annotate MRI images simultaneously. No data are downloaded, no software installed, allowing users to incrementally improve each other's work. This increases scientific efficiency, improves public data quality, and reduces redundant effort. We already index more than 8000 MRIs, which are ready for collaborative projects. To navigate this resource we developed MetaSearch, a meta-data filtering tool which makes it easy to find relevant data and projects to participate. Our virtual neuroimaging laboratory lowers the barriers for researchers, students, and citizen scientists to help scientific discovery.