Updated HAE Guidelines Explained: Role of Oral On-Demand Therapy скачать в хорошем качестве

Updated HAE Guidelines Explained: Role of Oral On-Demand Therapy

Updated hereditary angioedema guidelines place stronger emphasis on early on-demand treatment and individualized long-term prophylaxis. In this interview, Mauro Cancian, MD, PhD, a KONFIDENT investigator and from University of Padua, explains how phase 3 data on oral sebetralstat influenced the latest recommendations. Cancian discusses why timing of treatment remains critical, how oral therapy may reduce delays compared with injectable options, and how clinicians should interpret the guideline’s positioning of first-line on-demand therapies. He also addresses real-world adherence, breakthrough attacks despite prophylaxis, and remaining evidence gaps. Key highlights: 00:07: The most clinically meaningful change in the updated HAE guidelines 01:54: Emphasis on early, patient-controlled on-demand therapy 02:46: Key efficacy findings from KONFIDENT Read more about the guidelines here: https://www.hcplive.com/view/pediatri... #HAE #Allergy #HereditaryAngiodema