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This video explores the basis of gene therapy to unconventionally treat patients with Hemophilia A. Gene therapy is on the rise, providing a one-time treatment option compared to conventional practice. This video further explores the first gene therapy for Hemophiliacs under the brand name Roctavian. This video was made by McMaster students Sara Araz, Jaskaran Benepal, Alyssa Ciampa, and Aarchie Soni in collaboration with the McMaster Demystifying Medicine Program. Copyright McMaster University 2022 This video is provided for general and educational information only. Please consult your health care provider for information about your health. #Hemophilia #GeneTherapy #Roctavian #BloodDisorder #DemystifyingMedicine References: CDC. (2020, May 12). What is Hemophilia. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/hemophilia.... CDC. (2020, January 14). Treatment of Hemophilia. Centers for Disease Control and Prevention. https://www.cdc.gov/ncbddd/hemophilia... European Medicines Agency (EMA). (2022, June 24). First gene therapy to treat severe haemophilia A - European Medicines Agency. European Medicines Agency. https://www.ema.europa.eu/en/news/fir... Indiana Hemophilia & Thrombosis Center. (2022). Blood Clotting Factor Levels | Severity of Hemophilia. Ihtc.org. https://www.ihtc.org/severity-of-hemo... Nathwani, A. C. (2019). Gene therapy for hemophilia. Hematology, 2019(1), 1–8. https://doi.org/10.1182/hematology.20... NORD (National Organization for Rare Disorders). (2022, August 31). Hemophilia A. NORD (National Organization for Rare Disorders); NORD. https://rarediseases.org/rare-disease... 🎵 Song: 'Sappheiros - Dawn' is under a creative commons license license. / @sappheiros 🎶 Music promoted by BreakingCopyright: • 🛀 Calm Music (No Copyright) "Dawn" by @Sa...