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What Happens to Muscle When You Stop Eating

Discover exactly what will happen to your muscles when you stop eating for 1, 4, or even 30 days. Intermittent fasting can be very beneficial and can actually be used to preserve muscle. This video will show you exactly what happens to your muscles while fasting day by day at a microscopic level. 🔥 FREE 6 Week Shred: http://bit.ly/2Bv8CL4 📲 FREE Diet/Workout Planner Tool: http://bit.ly/2N41lTX What if I told you that you could stop eating for a day, two, or even three days, and not only keep your muscle but you might actually come out leaner, stronger, and have better insulin sensitivity? But then… what if you kept going? What if you didn’t eat for a week, or a month, or longer? Well, you probably already assume that’s when things change. In your mind, that’s when your body stops burning fat and starts burning you. Your strength slips, your recovery slows, and the very muscle you worked so hard to build becomes your body’s emergency fuel. So, where is that line where it goes from a net positive that helps you burn fat and reset, to a full blown negative? Well today we’re diving deep into what happens to your muscles day by day, from one to three to seven to thirty and beyond. And we’re not just talking about how your arms or chest will look in the mirror—we’re talking about what’s happening at the microscopic level, inside each muscle fiber, and inside every cell, as your body shifts from thriving to surviving. So let’s start at the beginning. Day one. You’ve skipped breakfast. Maybe lunch too. You're approaching the 16-hour mark, or even pushing a full 24-hour fast. At this stage, your body is calm. Glycogen, the stored form of carbohydrates in your liver and muscles, is still available. In fact, your liver glycogen is being used to keep your blood sugar stable, especially for your brain. Your muscle glycogen is largely untouched unless you're doing intense physical activity. And your insulin is dropping. This is beneficial because it allows stored body fat to become accessible as energy. Around this time, your body begins increasing norepinephrine and growth hormone, both of which support fat mobilization and help preserve lean tissue. Research shows that growth hormone can increase up to five times during short-term fasting. This hormone has powerful anti-catabolic properties. It protects your muscles, assists with fat burning, and enhances recovery. So how’s your muscle doing during those first 24 hours? Totally fine. Muscle size might look slightly reduced because glycogen stores begin to deplete, and those stores hold water, so you might look a little flatter. But it’s just a visual shift—your actual muscle tissue is still there. Strength and performance are unaffected. You could do an intense full-body workout day 1 and your body would still be in a state that prioritizes fat over muscle. Internally, your body is incredibly smart. It knows muscle is important. So early in the fast, it uses glycogen, free fatty acids, and a little bit of glucose from non-muscle sources to meet energy demands. Muscle breakdown is barely noticeable. If anything, short-term fasting can be a muscle-preserving tool, especially when you’re training during the fasted state and refeeding with adequate protein after 24 hours of fasting. This is also the phase where your mitochondria start adapting. Short-term fasting activates AMPK and increases the expression of a gene called PGC-1α, which stimulates the growth of new mitochondria in muscle. That means you actually get more efficient at producing energy, especially in endurance-based Type I fibers. It’s like giving your muscle cells a tune-up before the stress of starvation really kicks in. Autophagy, which is your body’s internal recycling system, will also start to increase. As you wrap up day one, and day two autophaghy clears out damaged proteins and cellular junk, which is a good thing for longevity and metabolic health. And it doesn't really touch muscle proteins yet. But now let’s move ahead to day three. You’ve gone 72 hours without food. Your glycogen is now almost fully depleted. Your liver glycogen is gone, and your muscle glycogen is low. Your body is relying on fat-derived ketones for fuel, especially for your brain. This is ketosis in action. It’s an amazing system—your body has adapted to starvation over millions of years, and this shift towards ketones for energy allows you to function without food while preserving lean mass. At this stage, ketones help reduce the body’s demand for glucose, and by doing so, those ketones reduce the need to break down muscle for energy. One of the most fascinating things about this stage is that ketones, especially a ketone body known as beta-hydroxybutyrate, actually suppress the enzyme that breaks down branched-chain amino acids like leucine. That means ketones help you spare muscle—chemically, not just functionally. So are you still preserving muscle? Mostly—yes. If you’re healthy, carrying enough body fat,