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This episode explores the latest evidence-based approach to diagnosing and treating subacromial shoulder pain and rotator cuff tendinopathy. Drawing on high-quality systematic reviews and international clinical guidelines, we explain why structured exercise therapy—particularly resistance training and motor control exercises—remains the first-line treatment for reducing pain and restoring function. We critically examine commonly used interventions such as arthroscopic subacromial decompression and corticosteroid injections, highlighting evidence showing no meaningful long-term advantage over conservative care. The discussion also covers best practices in diagnosis, emphasizing the value of clinical examination and ultrasound over routine MRI in early assessment. Finally, we address the role of manual therapy as an adjunct to exercise, the importance of patient education and shared decision-making, and how these factors influence outcomes, adherence, and patient satisfaction in modern shoulder rehabilitation.