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Discover how fasting extends lifespan, lowers insulin and blood sugar, reduces inflammation, regenerates gut cells, and promotes autophagy. Learn the science-backed benefits of fasting and how to implement strategic fasting protocols for metabolic health, cellular repair, and longevity. Nurse Doza breaks down when and how to use fasting as a powerful health tool. FEATURED PRODUCT Mitochondriac, featuring resveratrol with quercetin and methylated forms, is designed to support mitochondrial function and mimic the beneficial effects of fasting. Research shows resveratrol activates the same pathways as fasting—AMPK, SIRT1, and PGC-1α—promoting autophagy, mitochondrial biogenesis, and cellular repair. Pairing Mitochondriac with your fasting protocol enhances the metabolic benefits discussed in this episode, making fasting more sustainable and effective for longevity and energy production. 👉 Get Mitochondriac here: https://mswnutrition.com/products/mit... JOIN THE SCHOOL Struggling to know how long to fast, what to eat before and after, or how to troubleshoot when a fast doesn't feel right? Inside the School of Doza, you'll join a community of people implementing fasting protocols just like you—and get direct guidance during our Wednesday "Ask Me Anything" sessions that function like group consults. Bring your questions about fasting duration, supplement timing, breaking your fast properly, or interpreting your labs while fasting. Get real-time answers and avoid common fasting mistakes. Your first 7 days are completely free. 👉 Start your free trial: https://community.schoolofdoza.com/c/... 5 KEY TAKEAWAYS Fasting extends lifespan – Caloric restriction is the only known nutritional intervention proven to extend lifespan and reduce age-related disorders across multiple species by optimizing cellular metabolism. Fasting lowers insulin and blood sugar – After approximately 10 hours of fasting, stored glycogen is consumed and the body begins breaking down fatty acids, lowering fasting insulin levels and improving insulin sensitivity. Fasting reduces inflammation – Fasting decreases inflammatory markers including TNF-α, TGF-α, and PDGF, addressing the root cause of conditions like fatty liver, diabetes, autoimmune disorders, and heart disease. Fasting regenerates gut cells – Caloric restriction increases the number of intestinal stem cells and enhances the regenerative capacity of the injured intestinal epithelium, healing gut damage at the cellular level. Fasting promotes autophagy and mitochondrial biogenesis – Fasting activates the body's cellular cleanup process (autophagy) and stimulates the creation of new, healthy mitochondria through activation of PGC-1α, AMPK, SIRT1, and NOS pathways. TIMESTAMPS 00:00 – START 02:00 – What's happening at the School of Doza and weekly Ask Me Anything sessions 04:00 – Fasting extends lifespan through cellular metabolism optimization 08:00 – Fasting lowers insulin and blood sugar after 10 hours 12:00 – How resveratrol mimics fasting and enhances the fasting experience 15:00 – Fasting reduces inflammation across all body systems 19:00 – Fasting regenerates gut cells and heals intestinal damage 22:00 – Fasting promotes autophagy and cleans out toxic cells 26:00 – Mitochondrial biogenesis and the PGC-1α pathway activation 30:00 – Practical fasting protocol guidelines and implementation tips 35:00 – How to pair Mitochondriac with fasting for optimal results 38:00 – Join the School of Doza for fasting support and guidance RESOURCES Fasting and cellular metabolism optimization – https://pmc.ncbi.nlm.nih.gov/articles... Molecular effects of fasting on cellular metabolism – https://pmc.ncbi.nlm.nih.gov/articles... Calorie restriction and lifespan extension – https://www.sciencedirect.com/science... Calorie restriction reduces fasting insulin levels – https://pmc.ncbi.nlm.nih.gov/articles... Glycogen breakdown during starvation – https://www.sciencedirect.com/science... Resveratrol improves insulin sensitivity through SIRT1/AMPK pathway – https://www.sciencedirect.com/science... Calorie restriction enhances intestinal regeneration – https://pmc.ncbi.nlm.nih.gov/articles... Fasting and autophagy upregulation – https://pubmed.ncbi.nlm.nih.gov/30172... Calorie restriction promotes mitochondrial biogenesis – https://www.science.org/doi/10.1126/s... CONNECT 🔗 Connect with Nurse Doza: JOIN MY SCHOOL for FREE: https://community.schoolofdoza.com/c/... YouTube: / @schoolofdoza Instagram: / nursedoza Website: http://www.nursedoza.com/ LinkedIn: / jonathan-mendoza-dc-aprn-np-c-0609a038 TikTok: / nursedoza Twitter: / nursedoza