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How does research evidence actually make its way into practice? On episode 10 of season2, we're joined by guest co-host, doctoral student Nika Klaprat, to explore that question and more with implementation science pioneer Dr. Jeremy Grimshaw. From clinical guidelines to public health infrastructure, the conversation examines how implementation science helps bridge the gap between what we know works and what actually happens in practice. Drawing on their CIHR-funded research on protected cycling infrastructure and active transportation, the discussion explores a central question in modern health research: why do some evidence-based interventions succeed in practice while others fail to take hold? Dr. Grimshaw reflects on the evolution of implementation science from the evidence-based medicine movement and explains why generating strong evidence is only the beginning. The conversation also highlights his use of randomized controlled trials not just to test clinical interventions, but to test how clinical guidelines themselves are implemented and adopted in real-world settings. We highlight a challenge many trainees face when entering the field—navigating the many theories, models, and frameworks used in implementation science. From clinical guidelines to public health infrastructure, this episode highlights how implementation science helps bridge the gap between what we know works and what actually happens in practice. Papers & Resources That We Touched On In This Episode Effect of clinical guidelines on medical practice: a systematic review of rigorous evaluations: http://alturl.com/8dcyj De-implementing wisely: developing the evidence base to reduce low-value care: http://alturl.com/fy3f7 From best evidence to best practice: effective implementation of change in patients' care: http://alturl.com/p9h6x Improving stroke outcomes: http://alturl.com/2qu85 Implementation of evidence-based treatment protocols to manage fever, hyperglycaemia, and swallowing dysfunction in acute stroke (QASC): a cluster randomised controlled trial: http://alturl.com/7jsxj Mortality Reduction for Fever, Hyperglycemia, and Swallowing Nurse-Initiated Stroke Intervention: QASC Trial (Quality in Acute Stroke Care) Follow-Up: http://alturl.com/xz644 A guide to using the Theoretical Domains Framework of behaviour change to investigate implementation problems: http://alturl.com/tt6fp Consolidated Framework for Implementation Research (CFIR): http://http://alturl.com/bcyia The Consolidated Framework for Implementation Research (CFIR) User Guide: a five-step guide for conducting implementation research using the framework: http://alturl.com/5mrk8 RE-AIM: http://alturl.com/5vbc9 Understanding and applying the RE-AIM framework: Clarifications and resources: https://pmc.ncbi.nlm.nih.gov/articles... Our Co-Interviewer for the episode: Nika Klaprat: http://alturl.com/k8fxr Work from Dr. McGavock’s lab on implementing cycling infrastructure in Canada: http://alturl.com/nib9c Subscribe for new episodes ! Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/0lNr3Mj... Or find our episodes on: Soundcloud: / the_emerging_scholar umfm.com: https://umfm.com/series/the-emerging-...