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Recorded live on January 9th, 2024 In this recorded Urology Grand Rounds presentation, Stanford Urology Resident Dr. Anas Tresh discusses interstitial cystitis/bladder pain syndrome (IC/BPS) and the risk of vision changes with use of the oral medication Pentosan Polysulfate Sodium (PPS). Dr. Tresh begins by reviewing the condition itself, treatment approaches (such as PPS), AUA guideline recommendations, and findings from studies on associations between PPS and development of characteristic maculopathy. Dr. Tresh then highlights that IC/BPS lacks definitive treatments, and PPS usage potentially leading to irreversible retinal damage from pigmentary maculopathy, particularly with higher cumulative doses and longer duration of use. He concludes by emphasizing a focus on patient education about retinal risk before starting PPS and monitoring changes with eye exams during treatment. Claim CE credit at: https://stanford.cloud-cme.com/course... Learning Objectives: 1. Discuss IC/BPS and its treatment challenges. 2. Review PPS mechanisms of action and usage. 3. Summarize AUA guidelines on PPS retinal risks. 4. Discuss proactive measures and communication with patients regarding the risks associated with PPS treatment. Mitigation of Relevant Financial Relationships Stanford Medicine adheres to the Standards for Integrity and Independence in Accredited Continuing Education. For full disclosure information, please visit https://stanford.cloud-cme.com/course...