Stephen L Buchwald - Catalytic Processes for Carbon-Heteroatom Bond Formation скачать в хорошем качестве

Stephen L Buchwald - Catalytic Processes for Carbon-Heteroatom Bond Formation

Stephen L. Buchwald received his Sc.B. degree from Brown University (1977), working with Kathlyn A. Parker, David E. Cane, and Professor Gilbert Stork at Columbia University. He received his Ph.D. in 1982 from Harvard, with Jeremy R. Knowles, studying the mechanism of phosphoryl transfer reactions in chemistry and biochemistry. He was a postdoctoral fellow at Caltech with Professor Robert H. Grubbs, studying organotitanium chemistry. In 1984, he began as an assistant professor at MIT, where since 1997, he has been the Camille Dreyfus Professor. He has received numerous honors, including the Gustavus J. Esselen Award for Chemistry in the Public Interest in 2010, the 2013 Arthur C. Cope Award (ACS), the Linus Pauling Medal Award, and the Ulysses Medal (2014). He received the BBVA Frontiers in Knowledge Award in Basic Sciences (2014 Award). He also received the William H. Nichols Award from the New York ACS (2016). In 2018, he received the Tetrahedron Prize and the Dr. Karl Wamser Innovation Award (from the Technische Universität München). He was conferred the 2019 Roger Adams Award (ACS) and the 2019 Wolf Prize in Chemistry. In 2021, he was honored with the Huang Yaozeng Award in Organometallic Chemistry of the Chinese Chemical Society and the Inaugural Akira Suzuki Award (Hokkaido University). In 2022, he received the Paul Karrar Gold Medal from the University of Zürich. He is a fellow of the American Academy of Arts and Sciences and a National Academy of Science member. Abstract: Catalytic Processes for Carbon-Heteroatom Bond Formation The availability of general methods for carbon-heteroatom bond formation is central to modern-day organic synthesis. This lecture will focus on aspects of the work from our laboratory at MIT. It will describe several Pd- or Cu-catalyzed transformations relevant to the construction of molecular types of interest to those in academia and the pharmaceutical industry. A significant focus of the talk will be on the design, synthesis, and utilization of new ligands that can be used in a synthetically meaningful context. A comparison of the advantages/disadvantages of using a palladium or a copper catalyst as a function of substrate type will be discussed as part of the lecture. Learn more about The Welch Conference: https://welch1.org/conference/confere...