Basophilic Myelocyte and Basophilic band cell ; Stage, Location, Nucleus, Cytoplasm, Function скачать в хорошем качестве

Basophilic Myelocyte and Basophilic band cell ; Stage, Location, Nucleus, Cytoplasm, Function

developmental stages of basophils, focusing on the basophilic myelocyte and the basophilic band cell—two key steps in the maturation of these rare but powerful immune cells. 🧫 Basophilic Myelocyte Stage: First morphologically distinct precursor of basophils. Size: Large (18–20 µm). Nucleus: Round or oval, sometimes indented; occupies ~50% of the cell; chromatin is coarser and more granular than earlier stages. Cytoplasm: Pale blue with specific basophilic granules beginning to accumulate. Granules: Large, dark purple-black, uneven in size and shape; contain histamine and heparin. Mitosis: This is the last stage capable of cell division. Location: Found in bone marrow; very rare (0.5% of granulocytes). 🧬 Basophilic Band Cell Stage: Follows the basophilic metamyelocyte; just before the mature basophil. Size: Smaller (10–12 µm). Nucleus: Elongated, horseshoe-shaped or “U”-shaped; chromatin is condensed and heterochromatic. Cytoplasm: Pale blue-pink with abundant basophilic granules. Granules: Similar to mature basophils—contain histamine, heparin, and other inflammatory mediators. Mitosis: No longer capable of division. Function: Prepares for full immune functionality as a mature basophil3. 🔄 Developmental Sequence of Basophils Myeloblast Promyelocyte Basophilic Myelocyte Basophilic Metamyelocyte Basophilic Band Cell Mature Basophil #Basophil #Myelocyte #Basophilic #bandcell