What evidence supports using "natural" Mucuna pruriens (Velvet bean) in treating Parkinson's? скачать в хорошем качестве

What evidence supports using "natural" Mucuna pruriens (Velvet bean) in treating Parkinson's?

The Mucuna pruriens bean has been used in India (Africa, China) for centuries to address a syndrome that causes bradykinesia, tremors, and dementia. Interestingly, Levodopa was derived from Fava beans in 1913, but the Macuna bean has the highest concentration of levodopa (L-dopa), which is converted to dopamine in the brain. The amount of levodopa in these beans can range from 60 to 500 mg, and there is no regulation; in the USA and in many countries, mucuna is not regulated, so it is difficult to know how much you are consuming. This variability in dosages means that it is hard to maintain a steady state. While this may not be a problem at the beginning of the disease, after around five years, complications can arise. It is then important to seek expert help. When it comes to supplements, specifically Mucuna pruriens, I have a strong opinion. If you reside in the United States, there is no need to use this product, as there are potential “unknown” risks involved. However, if you feel that taking Mucuna is benefiting you, then there's no need to switch things up if it's working. For those residing in countries with limited resources, Mucuna can be an option, but it's crucial to seek guidance from a neurologist in your area. It is important to note that creating your own mucuna can be risky due to the potential presence of toxic elements in some mucuna plants. The literature has numerous instances of toxicity caused by ingestion. As for whether I would take Mucuna pruriens if I had Parkinson's disease, my answer is NO. Instead, I would opt for Rytari or Sinemet (carbidopa-Levodopa) in combination with a well-designed exercise program and a balanced diet. Dr. Z