Episode 372: Pharmacology 101: Proteasome Inhibitors скачать в хорошем качестве

Episode 372: Pharmacology 101: Proteasome Inhibitors

"The proteasome itself, it really helps us unfold or get rid of misfolded proteins or degradations of different cells. We used to have garbage disposals in our sinks, and we used to put food product in there. If your garbage disposal is clogged, then everything backs up. So that's kind of what's really going on in the cell itself, is that I'm building up these unnecessary proteins that we should be getting rid of, and it actually causes apoptosis or cell death," ONS member Daniel Verina, DNP, RN, ACNP-BC, nurse practitioner for the multiple myeloma program at Mount Sinai Medical Center in New York, NY, told Lenise Taylor, MN, RN, AOCNS®, BMTCN®, oncology clinical specialist at ONS, during a conversation about the proteasome inhibitor drug class. Music Credit: "Fireflies and Stardust (http://www.incompetech.com/) " by Kevin MacLeod Licensed under Creative Commons by Attribution 3.0 Earn 0.75 contact hours (including 40 minutes of pharmacotherapeutic content) of nursing continuing professional development (NCPD) by listening to the full recording and completing an evaluation at courses.ons.org by July 18, 2026. The planners and faculty for this episode have no relevant financial relationships with ineligible companies to disclose. ONS is accredited as a provider of nursing continuing professional development by the American Nurses Credentialing Center's Commission on Accreditation. Learning outcome: Learner will report an increase in knowledge related to the use of proteasome inhibitors in the treatment of cancer. Episode Notes • Complete this evaluation for free NCPD (https://loginlr.ons.org/sso/jwt/redir...) . • ONS Podcast™ Pharmacology 101 series (https://www.ons.org/search?ons_global...) • ONS Voice article: AI Multiple Myeloma Model Predicts Individual Risk, Outcomes, and Genomic Implications (https://www.ons.org/publications-rese...) • ONS books: • Chemotherapy and Immunotherapy Guidelines and Recommendations for Practice (https://www.ons.org/store/books/chemo...) (second edition) • Clinical Guide to Antineoplastic Therapy: A Chemotherapy Handbook (https://www.ons.org/store/books/clini...) (fourth edition) • Guide to Cancer Immunotherapy (https://www.ons.org/store/books/guide...) (second edition) • Multiple Myeloma: A Textbook for Nurses (https://www.ons.org/store/books/multi...) (third edition) • Clinical Journal of Oncology Nursing article: Optimizing Transitions of Care in Multiple Myeloma Immunotherapy: Nurse Roles (https://doi.org/10.1188/25.CJON.E7-E16) • Oncology Nursing Forum articles: • Changes in Health-Related Quality of Life During Multiple Myeloma Treatment: A Qualitative Interview Study (https://doi.org/10.1188/23.ONF.635-645) • Facilitators of Multiple Myeloma Treatment: A Qualitative Study (https://doi.org/10.1188/23.ONF.372-380) • ONS Guidelines™ and Symptom Interventions • Adherence to Oral Anticancer Medication (https://www.ons.org/clinical-tools/pe...) • Peripheral neuropathy (https://www.ons.org/clinical-tools/pe...) • ONS Hematology, Cellular Therapy, and Stem Cell Transplantation Learning Library (https://www.ons.org/hematology-cellul...) • American Society of Hematology (https://www.hematology.org/) • International Myeloma Foundation (https://www.myeloma.org/) • Leukemia and Lymphoma Society (https://www.lls.org/) • Multiple Myeloma Research Foundation (https://themmrf.org/) To discuss the information in this episode with other oncology nurses, visit the ONS Communities (http://communities.ons.org/) . To find resources for creating an ONS Podcast club in your chapter or nursing community, visit the ONS Podcast Library (https://www.ons.org/learning-librarie...) . To provide feedback or otherwise reach ONS about the podcast, email pubONSVoice@ons.org (mailto:pubONSVoice@ons.org?subject=Website%20feedback%20from:%20Oncology%20Drug%20Reference%20S...