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💡 Action Potentials EXPLAINED: K⁺ Channels, Ion Exchangers & Genetic Regulation (USMLE High-Yield Beginner’s Guide) Ever wondered how our cells generate and propagate action potentials? In this video, we dive deep into the mechanisms of ion channels—including K⁺ channels (Ks, Kr, Kur, and the inward rectifier current) and important ion exchangers—and explore the genes that regulate these processes. Perfect for medical students, physiologists, and anyone preparing for USMLE or board exams! What You’ll Learn in This Video: ✔️ K⁺ Channel Types: How Ks, Kr, and Kur channels, along with inward rectifiers, shape the action potential ✔️ Ion Exchangers & Transporters: Their roles in maintaining ionic balance during depolarization and repolarization ✔️ Genetic Regulation: Key genes involved in the expression and function of these ion channels ✔️ Clinical Relevance: High-yield exam tips and mnemonics for USMLE & board exams ⏰ Timestamps for Easy Navigation: 00:00 Resting potential PHASE 4 00:27 Depolarization PHASE 0 01:18 SCN5A gene and Long QT type 3 01:58 Repolarization PHASE1 02:27 KCND3 gene and ischemia and heart failure 02:49 Plateau PHASE 2 03:20 CACNA1C gene and Long QT type 8 Timothy syndrome 04:10 K slow channel 04:32 KCNQ1 and KCNE1genes Long QT type 1 and 5 05:36 Distribution of K slow channel in myocardium 06:39 Ultra rapid potassium channel 06:50 KCNA5 gene and familiar atrial fibrillation 07:39 Late Sodium current 08:15 Repolarization PHASE 3 08:25 K rapid current 08:46 KCNH2 gene and Long QT type 2 09:28 Inward rectifer potassium current 09:52 KCNJ2 gene and Long QT type 7 Andersen-Tawil syndrome 10:43 Na/K Pump 11:30 Ca/Na Exchanger 💬 Question for You: Which ion channel mechanism do you find most challenging to understand—K⁺ channel diversity or ion exchanger functions? Let us know in the comments below! 😊 👍 Help Us Grow: Like this video if you found it helpful Subscribe for more high-yield medical and physiology content Share this video with classmates or colleagues! ⚠️ Disclaimer: This video is intended for educational purposes only and does not replace professional medical advice. Always consult a healthcare provider for clinical decisions. Our telegram channel with the quizes, ECG, books and other staff https://t.me/foxterRier_med #usmle #step1 #step2 #medicine #pathology #physiology #education #medicalschool #pharmacology #biochemistry #highyield #lab