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For years, transfusing O+ whole blood or PRBCs to females of childbearing age has been considered a major clinical no-go — based on the risk of alloimmunization and hemolytic disease of the fetus and newborn (HDFN). But is this long-standing concern still justified in the context of modern emergency care? In this powerful and eye-opening webinar, Katie Shanahan and Molly Sherwood — both alloimmunized patients themselves — walk us through the true risks, latest evidence, and evolving guidelines on the use of Rh-positive blood products in women of childbearing potential. They provide personal insights and data that challenge traditional views and offer clarity for EMS systems navigating this controversial issue. Whether you're a medical director, flight crew, EMS provider, OB team, or trauma clinician, this conversation is essential viewing as whole blood continues to expand in prehospital settings.