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Quantitative Magnetic Resonance Imaging Conference: Applications in Neurodegeneration (October 26-28th 2022) T2* and QSM - Methods Keynote Dr. Jongho Lee - Advanced susceptibility imaging Biography: Dr. Jongho Lee is Professor at the Department of Electrical and Computer Engineering, Seoul National University. He received his B.S from Seoul National University (1998) and M.S-Ph.D at Stanford University (2007) all in Electrical Engineering. He worked at National Institutes of Health as a research fellow (2007 to 2010) and then at the Department of Radiology, University Pennsylvania as Assistant Professor (2010 to 2014). In 2014, he moved back to Seoul National University to join a faculty position. He has been active in international societies, chairing Electro-Magnetic Tissue Properties Study Group at ISMRM, serving as an annual meeting program committee for ISMRM, and working as an editorial board member of NeuroImage, etc. He gave a number of invited presentations at international workshops and conferences including a most recent plenary talk at ISMRM (2021). Abstract: Myelin and iron are important substances for normal functions of the brain. The changes in their local concentrations have been reported in multiple brain disorders (e.g. demyelination in multiple sclerosis and iron deposition in deep gray matter in Parkinson’s disease). Hence, imaging their concentrations quantitatively using MRI allows us to monitor the condition of the brain in-vivo and has been an important topic of research. In this presentation, I will introduce an advanced magnetic susceptibility mapping method, which is referred to as χ-separation, as a potential tool to quantitatively visualize myelin and iron in the brain. Physics behind the imaging methods will be introduced and reconstruction will be followed. Finally, validation using simulation and phantom are provided along with applications to in-vivo and ex-vivo human brains and MS patients. You can follow the qMRI Conference on Twitter @qMRI_conference Organizing Committee Dr. Mallar Chakravarty (@mallarchkrvrty1) Dr. Christine Lucas Tardif (@tardiftweets) Dr. Christopher Rowley (@rowleycd) Aurélie Bussy (@AurelieBussy) Olivier Parent (@oparent41)