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Children in territories controlled by the Islamic State across Syria and Iraq have endured severe, multi-layered trauma, with profound effects on their mental health and social well-being. Trauma and post-traumatic stress disorder (PTSD) not only alter brain development but also disrupt emotional, behavioral, and cognitive functioning, potentially leading to long-term impairments and, if untreated, the development of antisocial behaviors. The repatriation and reintegration of these children present complex challenges, requiring a coordinated, multidisciplinary response. In this session, Dr. Heidi Hellis and Dr. Emma Cardeli provide insights into the challenges and opportunities associated with repatriation and reintegration efforts. The discussion highlighted the psychological toll on children, particularly the connection between trauma, PTSD, and long-term recovery. The session placed emphasis on the importance of early intervention, community involvement, and individualized approaches to meet the unique needs of children, especially those in vulnerable circumstances. Speakers Dr. Heidi Ellis, Associate Professor in Psychology and Psychiatry at Harvard Medical School and Boston Children’s Hospital; Director of the Refugee Trauma and Resilience Center at Boston Children’s Hospital Dr. Emma Cardeli, Refugee Trauma and Resilience Center, Boston Children’s Hospital Sarah Franck, United Nations Office of Counter-Terrorism Larissa Adameck, United Nations Office of Counter-Terrorism