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Automated Gel Filtration Desalting & Buffer Exchange https://www.biotage.com/gel-filtratio... PhyTip gel filtration desalting columns operate as small scale, chromatographic separation columns. They are the only high throughput, automated, chromatography desalting solution. Similar to the PhyTip affinity columns, the resin of choice is positioned between two inert screens that maintain the resin bed at the base of the column. Unlike the affinity columns, the sample is passed unidirectionally through the column by gravity flow. High Performance: Remove more than 95% of salts with more than 80% yield of protein Retain protein functionality Less than 10% CV for volume and concentration between final samples Ready for downstream assay Automated desalting/buffer exchange of functional proteins: Fully automated process with MEA Personal Purification System 12 or 96 samples desalted/buffer exchanged in ~30 minutes. High throughput format: Available in 96 sample format for high throughput processing PhyTip columns are compatible with most 8, 12, and 96-channel automation liquid handling robots including Agilent Technologies, Beckman Coulter, Dynamic Devices, Perkin Elmer, Hamilton, and Tecan.