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The Origin of Aspirin: From Willow Bark to the Pharmacy Shelf

In this video, Patrick Kelly tells the story of aspirin, the iconic painkiller tablet, from its ancient origins with willow bark aspirin to modern pharmacology. Learn how aspirin is prepared from salicylic acid and see how it compares to other popular pain relievers like ibuprofen and Tylenol (acetaminophen/paracetamol). Since a few people have asked, the shirt is a rugby shirt from ‪@RowingBlazers‬ ☠️NONE OF THE INFORMATION IN THIS VIDEO SHOULD BE USED AS MEDICAL ADVICE OR OPINION. IT IS FOR GENERAL EDUCATION AND ENTERTAINMENT☠️ 🔗 L I N K S 🔗 📱Instagram:   / patkellyteaches   🐦Twitter:   / patkellyteaches   💰Patreon:   / corporis   🔬Old channel:    / corporis   📚My favorite books https://docs.google.com/document/d/1w... 🔑 P A T R O N S 🔑 Oxytocin Tier: Mike W | Joanne K | Jim C Jr. | Jody O | Paul R | Daphne P | Oli W Growth Hormone Tier: Dane M | Brendan P | Brandon K | Richardion G | Joe B | Mindi F | Sal F | Michael G | Brian B | Eileen H | Waffles the Dog | Brian T | Brian H | Michael R | Karen S | Sarah B | Robin B | Jacob S | Hyeon-S | Pranav M | Paul | Lucy Fur | huynhy | elnombre91 | Alcedo | Magmania | Josef K | Kyle K | Dab Brills | Robert M | Kristal C | Unsalted Pecan | Jiggs | TierZoo | Skasi | Jane G | Jack M | Hailey H | Matthew B | Michelle J | Helena SB | Eric L | Marshall K | David S | Ryne CJ | Kilian | Dean M | Ben | Cody S | Michelle L | Joseph G | Aryan Y | GD Annin | Vic K | Becca S | StealthyInk | Jesse B | Aleksander F | gidoo | Roxana A | Marc M | Munsu J | Doyle V 📜 S O U R C E S 📜 Annotated fact checked script on Patreon:   / 110687991   The Drug Hunters (affiliate link) https://amzn.to/3SCfoDP The Discovery of Aspirin's Antithrombotic Effects (2007) https://www.ncbi.nlm.nih.gov/pmc/arti... The first 3500 years of aspirin history from its roots – A concise summary (2019) https://www.sciencedirect.com/science... Traveling through time with aspirin, a healing companion (2011) https://journals.sagepub.com/doi/pdf/... The discovery of aspirin: a reappraisal (2000) https://www.ncbi.nlm.nih.gov/pmc/arti... Rev Stone Willow paper (1763) https://royalsocietypublishing.org/do... THE LIFE CYCLE OF STERLING DRUG, INC. (2000) https://acshist.scs.illinois.edu/bull... Prostaglandin in the inflammatory response https://www.ncbi.nlm.nih.gov/pmc/arti... Painkillers and prostaglandins (2003) https://www.nature.com/articles/nsb04... ASPIRIN IN THE TREATMENT OF VASCULAR DISEASES (1948) https://www.sciencedirect.com/science... Release of Additional Factors in Anaphylaxis and its Antagonism by Anti-inflammatory Drugs (1969) https://www.nature.com/articles/223029a0 1974 Elwood trial https://www.ncbi.nlm.nih.gov/pmc/arti... Aspirin as a Therapeutic Agent in Cardiovascular Disease : A Statement for Healthcare Professionals From the AHA (1997) https://www.ahajournals.org/doi/full/... Pharmacology of ibuprofen https://www.ncbi.nlm.nih.gov/pmc/arti... The development of COX2 inhibitors (2003) https://www.nature.com/articles/nrd1034 Future of COX-2 inhibitors (2005) https://www.nature.com/articles/nrd17... VIGOR study (2000) https://www.nejm.org/doi/full/10.1056... The sad story of Vioxx, and what we should learn from it (2004) https://www.ccjm.org/content/ccjom/71... ISIS-2 (1998) https://www.bmj.com/content/bmj/316/7... 💻 C O N T A C T 💻 patkellyteaches [at] gmail.com ⌛T I M E S T A M P S ⌛ 0:00 intro 0:32 How did Aspirin come from Willow? 8:45 Bayer's Marketing Plan 15:22 Mechanism of Action 17:57 Pharmacology of aspirin 🎵M U S I C🎵 Backed Vibes Clean - Rollin at 5 by Kevin MacLeod is licensed under a Creative Commons Attribution 4.0 license. https://creativecommons.org/licenses/... Source: http://incompetech.com/music/royalty-... Artist: http://incompetech.com/ #historyofmedicine #medicalhistory