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The hormonal changes and hot flashes that accompany menopause are familiar to most women, but the accompanying brain changes have not received as much attention. We now know that the inflammatory responses associated with declining levels of estrogen have neurological consequences, which could explain why women are more likely than men to develop Alzheimer’s disease. The author of The Menopause Brain talks about new approaches to hormone replacement therapy and the targeted lifestyle changes that could help women thrive during this physiological and emotional transition—and perhaps safeguard against dementia as well. Jennifer Ashton Lisa Mosconi Aspen Ideas: Health takes place on the Aspen Institute’s wondrous 40-acre campus in the Rocky Mountains from June 20-23, 2024. The three-day event, which has opened the renowned Aspen Ideas Festival since 2014, is where health’s biggest challenges meet its biggest thinkers. #AspenIdeasHealth #AspenIdeas For more information about Aspen Ideas: Health, visit https://www.aspenideas.org/attend/health.