Prof. Mikael Palner, Psychedelics induce long-term altered metabolic activity and connectivity ... скачать в хорошем качестве

Prof. Mikael Palner, Psychedelics induce long-term altered metabolic activity and connectivity ...

Talks from the ESI Systems Neuroscience Conference (ESISyNC) 2025: Not your ordinary brain: Altered states of consciousness and their neural basis ► ESISyNC 2025 Playlist: https://studio.youtube.com/playlist/P... ► Last year's ESISyNC Playlist:    • ESI SyNC 2024 | ESI Systems Neuroscience C...   Serotonergic psychedelics have shown promising benefits in studies of various neuropsychiatric disorders. While their acute effects last only a few hours, the positive therapeutic effects can persist long after a single administration. Serotonergic psychedelics produce their psychedelic effects by activating serotonin 2A receptors, but differ in other pharmacological aspects. To guide the safest and most effective treatment for specific neuropsychiatric disorders, it is crucial to gain a better understanding of the different acute and long-term effects of these drugs on the living brain. In his talk, Prof. Mikael Palner illustrates how three different serotonergic psychedelics—psilocybin, LSD, and 2C-B—induce different acute and long-term patterns in metabolic activity and connectivity. These findings provide insights into the mechanisms underlying the therapeutic effects of psychedelic substances in neuropsychiatric disorders, improve our understanding of how they alter stress resilience, and offer guidance on which drugs may be useful for specific psychiatric disorders.   / esi_frankfurt     / esi_frankfurt     / ernst-struengmann-institute   https://www.esi-frankfurt.de/