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When writing software to process health, genetic or other sensitive data in High Performance Computing (HPC) clusters, software developers and researchers must consider the requirements of the General Data Protection Regulation, including the principle of privacy by design and the duties of data protection. In this webinar we will highlight the risks of working with sensitive data on an HPC cluster and what are common software vulnerabilities. We will discuss general best practices in software development and provide guidelines on how to handle data in applications. We will also raise awareness of outside factors that affect data security and briefly mention important generic organisational measures that should be in place. Speaker: Sarah Peter, Luxembourg Centre for Systems Biomedicine (University of Luxembourg) All materials are free cultural works licensed under a Creative Commons Attribution 4.0 International (CC BY 4.0) license, except where further licensing details are provided.