Polyphron CEO Matthew Osman on his Computation-First Tissue Foundry скачать в хорошем качестве

Polyphron CEO Matthew Osman on his Computation-First Tissue Foundry

Polyphron is led by co-founder and CEO Matthew Osman, a twice-exited tech entrepreneur turned biotech founder. Matthew is building a computation-first tissue foundry that applies AI and lab automation to semi-autonomously replicate human tissues in a dish. Polyphron aims to create the world’s most efficient tissue foundry for regenerative medicine. Listen to this episode to learn more about the core bet and technological platform at Polyphron, the remarkable progress they’ve made on two programs in heart and brain tissue in just a year, and what’s next for the company. 0:00 Intro 2:08 Why most tissue engineering fails (and why structure is everything) 7:49 Small tissue grafts that stop organ collapse before it starts 11:12 My personal health scare that made me see the massive value of human tissue 14:43 Understanding Polyphron’s platform 31:01 Autologous versus allogeneic approaches 35:22 Two breakthrough experiments 44:34 The business model that can lead to a trillion dollar biotech