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Do you find that the wait for bad news is often more painful than the news itself? According to the sources, the human brain functions as an "anticipation machine," whose primary goal is to predict the future to increase our chances of survival. In this video, we dive deep into the neurobiology of anxiety to understand why uncertainty is one of the most stressful states a human can experience. In this video, we explore: • The Power of Uncertainty: Learn why the inability to predict a threat prevents us from avoiding or mitigating it, leading to chronic anxiety. Studies even show that people often find known negative outcomes less stressful than uncertain ones. • Evolutionary Mismatch (Adaptive Lag): Discover how psychological mechanisms that helped our hunter-gatherer ancestors survive are now mismatched with the modern world. This "adaptive lag" explains why modern social competition and media images can lead to decreased self-esteem or health issues like diabetes. • The Neural Circuitry of Fear: We break down how the extended amygdala (including the Ce and BST) processes both certain and uncertain threats. • The Default Mode Network (DMN) & Rumination: Understand how the system meant for dreaming can "hijack" the mind, causing us to obsessively chew over anxious thoughts about the past or future. • The UAMA Model: An integrated look at the five maladaptive processes of pathological anxiety: overestimating threat cost, hypervigilance, safety learning deficits, avoidance, and heightened reactivity to uncertainty. • Environmental Impact: How external factors like industrial and transport noise can physically raise cortisol levels and trigger long-term stress symptoms.