Endogenous Opioids (Opioid peptides) Definition, Function, Types; Endorphins, Enkephalins, Dynorphin скачать в хорошем качестве

Endogenous Opioids (Opioid peptides) Definition, Function, Types; Endorphins, Enkephalins, Dynorphin

Endogenous opioids are naturally occurring peptides in the body that function similarly to opioid drugs by binding to opioid receptors. They play a crucial role in regulating pain, mood, and various physiological processes. Here are some key points about endogenous opioids and opioid receptors: Endogenous Opioids Types: The main types of endogenous opioids are enkephalins, endorphins, and dynorphins. Enkephalins: Pentapeptides involved in regulating pain and nociception. Endorphins: Peptides produced in the brain and pituitary gland, known for their pain-relieving and mood-elevating effects. Dynorphins: Peptides that have potent effects on pain perception and stress response. Opioid Receptors Mu (μ) Receptors: Primarily involved in pain relief, euphoria, and respiratory depression. Endorphins and enkephalins have a high affinity for mu receptors. Delta (δ) Receptors: Associated with pain modulation and mood regulation. Enkephalins bind strongly to delta receptors. Kappa (κ) Receptors: Involved in pain relief and dysphoria. Dynorphins have a high affinity for kappa receptors. Functions of Endogenous Opioids Pain Relief: By binding to opioid receptors, endogenous opioids inhibit the transmission of pain signals, providing natural analgesia. Mood Regulation: They play a role in regulating mood and emotional responses, contributing to feelings of pleasure and well-being. Stress Response: Endogenous opioids are involved in the body's response to stress, helping to reduce anxiety and promote relaxation. Immune Modulation: They can influence the immune system and inflammatory responses. Understanding the role of endogenous opioids in the body has significant implications for pain management, mental health, and overall well-being. These naturally occurring peptides are essential for maintaining balance and responding to various physiological challenges. #Opioids