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Dr. Chris Palmer, assistant professor of psychiatry at Harvard Medical School, joins me to discuss the relationship between metabolic function and mental illness. We begin with Dr. Palmer’s work with patients suffering from severe conditions like schizophrenia and schizoaffective disorder, psychiatry’s current challenges with treatment-resistant conditions, and the important distinction between difficult psychological states and brain-based disorders. We then explore the relationship between mental illness and metabolic function, the key role mitochondria play in the process, and how current treatments impact our metabolism. Dr. Palmer and I close the episode by discussing a number of practical interventions to improve metabolic function, including the ketogenic diet, sleep, exercise, stress management techniques like mindfulness practice, and even love, connection, and sense of purpose. Key Topics: 0:00 Introduction 1:30 How Dr. Palmer's personal experience has influenced his work 4:00 The brain energy theory as a response to treatment resistant conditions 9:35 Mental states vs. mental disorders, and problems with our diagnostic criteria 15:05 Brain disorders as metabolic disorders 20:30 Defining metabolism 23:25 The role of mitochondria 29:35 How medication affects metabolism 35:25 How stress and emotions affect metabolism 42:00 The ketogenic diet, mitophagy, and mitochondrial biogenesis 48:05 The importance of education and support around ketosis for medical conditions 53:30 Supplementing medication with lifestyle change vs. replacing it 57:00 Sleep and light exposure 1:00:15 Love, connection, and sense of purpose 1:07:15 A sense of safety as a prerequisite for healing 1:10:10 Recap Subscribe to Being Well on: Apple Podcasts: https://podcasts.apple.com/us/podcast... Spotify: https://open.spotify.com/show/5d87ZU1... Who Am I: I'm Forrest, the co-author of Resilient (https://amzn.to/3iXLerD) and host of the Being Well Podcast (https://apple.co/38ufGG0). I'm making videos focused on simplifying psychology, mental health, and personal growth. You can follow me here: 🎤 https://apple.co/38ufGG0 🌍 https://www.forresthanson.com 📸 / f.hanson