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In this episode of Revolution Health Radio, Chris Kresser explains why vitamin D supplementation should never be one-size-fits-all. Drawing on new research—including a groundbreaking study on magnesium’s regulatory role—Chris explores how genetics, ethnicity, body weight, age, health status, sun exposure, and nutrient cofactors all shape an individual’s vitamin D needs. He outlines optimal testing strategies, safe and effective target ranges, and the critical roles of magnesium, vitamin K2, and vitamin A in vitamin D metabolism. The episode reframes vitamin D optimization as a personalized, systems-based approach that prioritizes balance, testing, and real-world physiology over generic dosing guidelines. In this episode we discuss: --Why standard vitamin D recommendations don’t work for most people --The impact of obesity, aging, gut health, liver function, and kidney health --Optimal vitamin D blood levels—and why more is not always better --The U-shaped risk curve of vitamin D deficiency and excess --Why testing and seasonal retesting are essential --Magnesium’s newly discovered role as a “vitamin D thermostat” --Sun exposure benefits beyond vitamin D production --How to personalize supplementation based on labs and lifestyle Show Notes: --Links to all of the studies mentioned in this podcast can be found here: https://chriskresser.com/vitamin-d-wh... --If you’d like to ask a question for Chris to answer in a future episode, submit it at https://chriskresser.com/podcastquest... Add back in what the modern world has crowded out and feel and perform your best with the line of Adapt Naturals supplements. Learn more and place your order at https://AdaptNaturals.com. READ FULL ARTICLE: https://chriskresser.com/vitamin-d-wh... FACEBOOK: / chriskresserlac TWITTER: / chriskresser INSTAGRAM: / chriskresser UNCONVENTIONAL MEDICINE: https://unconventionalmedicinebook.com/ THE PALEO CURE: http://paleocurebook.com TAKE BACK YOUR HEALTH: http://chriskresser.com SUBSCRIBE FOR MORE VIDEOS: http://www.youtube.com/subscription_c... Chris Kresser M.S., L.Ac. is the co-founder of the California Center for Functional Medicine, the founder of Kresser Institute, the host of the top-ranked health podcast Revolution Health Radio, the creator of ChrisKresser.com, and the New York Times best-selling author of The Paleo Cure and Unconventional Medicine. He is one of the most respected clinicians and educators in the fields of Functional Medicine and ancestral health and has trained over 2,000 clinicians and health coaches from more than 50 countries in his unique approach. Chris was named one of the 100 most influential people in health and fitness by Greatist.com and has appeared as a featured guest on Dr. Oz, Time, The Atlantic, NPR, Fox & Friends, and other national media outlets. Throughout his career, Chris has been devoted to exploring the deeper questions surrounding health and wellness. His most recent work is focused on helping people to thrive and flourish even in the midst of chronic illness or other challenging circumstances. He recently launched Adapt Naturals, a supplement line designed to add back in what the modern world has squeezed out and help people perform and feel their best. The Revolution Health Radio Show is brought to you by Adapt Naturals and ChrisKresser.com.