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Just how much exercise is 'too much'? Do extreme levels of physical activity have detrimental effects on your health or is the notion largely a myth? Join us as we delve into an evolutionary perspective on exercise, mortality, and their complex relationship. In this comprehensive video, we explore numerous studies involving both elite athletes and non-athletes, revealing some surprising findings about exercise doses and their impact on mortality. We also tackle the 'Open Window Hypothesis', an age-old concern linking rigorous exercise to a temporary weakened immune system. Ever wondered about the reports of heart damage in marathon runners and endurance athletes? We debunk some misconceptions surrounding high coronary artery calcium (CAC) scores among athletes and 'Athlete's Heart', providing insight into why these could actually be protective adaptations rather than signs of pathology. Don't miss the evidence-based conclusion on the question of 'too much exercise', and understand why the negative effects of too little exercise far outweigh those of too much. Tune in and find out the optimal balance for your health. 0:00 Introduction 1:20 The effect of "too much" exercise on the immune system: the open window hypothesis 3:00 Overexercise and the heart 4:25 An evolutionary perspective on plaque formation 4:45 Coronary artery calcium scores and mortality risk 5:20 The Athlete's heart 6:07 Conclusions #Exercise #Health #Fitness #Endurance #CardioHealth #ExerciseMyths #HealthyLifestyle #EnduranceTraining #cardiovascularhealth References (in order of appearance): https://doi.org/10.1186/s40798-015-00... https://doi.org/10.1001/jama.1996.035... https://doi.org/10.1001/archinte.163.... https://doi.org/10.1016/j.jacc.2014.0... https://doi.org/10.1001/jamainternmed... https://pubmed.ncbi.nlm.nih.gov/6623247/ https://pubmed.ncbi.nlm.nih.gov/2266764/ https://pubmed.ncbi.nlm.nih.gov/20839... https://doi.org/10.3389/fimmu.2018.00648 https://doi.org/10.1007/s12026-014-85... http://dx.doi.org/10.1016/j.bbi.2013.... https://doi.org/10.1086/606014 https://doi.org/10.1161/CIRCULATIONAH... https://doi.org/10.1001/jamacardio.20... https://doi.org/10.1016/j.amjmed.2018...