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Hidden Causes of High B12: Mast Cell Activation Syndrome & SIBO Explained Are you puzzled by high B12 levels without taking any supplements? This video dives into often-overlooked causes of elevated B12 and explores why you might still experience symptoms like fatigue and fogginess. **WORK WITH ME ⭐️ : https://www.swintegrativemedicine.com... **My Book: Don't B12 Deficient https://geni.us/rTQTvd (amazon link) ** We breaks down how Mast Cell Activation Syndrome (MCAS) and Small Intestinal Bacterial Overgrowth (SIBO) contribute to deceptive B12 readings and what it means for your health. Discover the key differences between various B12 binding proteins, such as Transcobalamins, and understand why functional tests like methylmalonic acid and homocysteine are critical. Understanding the intricacies of these conditions is key to decoding your confusing B12 levels and addressing the root cause of your symptoms. First, We explain Mast Cell Activation Syndrome (MCAS), a condition where mast cells become overactive and release a flood of immune chemicals, leading to an increase in specific B12 binding proteins. This mechanism can trap B12 in the bloodstream, making it unavailable to your cells. Next, we delve into Small Intestinal Bacterial Overgrowth (SIBO), where bacteria that don’t belong in the small intestine produce B12 or B12 analogs. These bacteria can also create an ideal environment for an excess of these binding proteins, further complicating B12 absorption. These two conditions, are linked showing how SIBO can trigger MCAS to create a perfect storm that leaves you with high serum B12 but deficient at the cellular level. he stresses the importance of functional markers to truly understand your B12 status. 00:00 Introduction: The Mystery of High B12 Levels 00:55 Understanding B12 and Its Cellular Role 02:09 Hidden Cause 1: Mast Cell Activation Syndrome (MCAS) 04:01 Hidden Cause 2: Small Intestinal Bacterial Overgrowth (SIBO) 06:20 Linking MCAS and SIBO: A Perfect Storm 07:43 Conclusion: Digging Deeper into High B12 Levels 08:21 Next Steps: High B12 and Cancer Risk