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Can a humble fiber molecule train your immune system to age better? In this episode of New Frontiers in Functional Medicine, I sit down with Robert Rountree, MD and Chris D’Adamo, PhD to unpack the wildly underappreciated world of beta-glucans through a longevity and immune resilience lens. We cover what beta-glucans are, how their unique 3D triple-helix structure lets them “dock” onto immune receptors like CR3, Dectin-1, and toll-like receptors, and why that matters for immune balance, vaccine responsiveness, cancer support, detox, mood, and healthy aging. You’ll hear about: The different beta-glucan structures (1,3 / 1,6 vs 1,4) and why source matters (yeast, mushrooms, oats, seaweed) How beta-glucans help “wake up” immune cells without overstimulating them, and why that’s relevant in autoimmunity Immunosenescence & inflammaging: what happens to immune cells as we age, and how beta-glucans may help Clinical data on beta-glucans as adjuncts in cancer care and their impact on vaccine responsiveness in older adults A new TruDiagnostic beta-glucan trial looking at immune age and biological age How beta-glucans may support detox (PFOAs, mold), gut barrier integrity, microbiome health, cortisol, fatigue, and mood Why dosing, product quality, and purity matter, including trial data on BWHLabs‘ highly purified and bioavailable BWH-85™ formulation How Dr. Rountree is using beta-glucans as a true “workhorse” nutrient in clinical practice If you’re a clinician, biohacker, or just longevity-curious, this is a deep dive into a molecule that deserves a front-row seat in your immune and aging toolbox. #BetaGlucan #ImmuneResilience #Immunosenescence #Inflammaging #LongevityMedicine #FunctionalMedicine #DrKaraFitzgerald #NewFrontiersPodcast Check out the show notes at https://www.drkarafitzgerald.com/fxme... for the full list of links and resources. GUEST DETAILS Bob Rountree, MD, is a leading figure in integrative and functional medicine with more than 40 years of clinical experience. Medical Director of Boulder Wellcare and long-time IFM faculty, he is widely published and a respected educator in personalized medicine, botanical therapies, and immune health. Chris D’Adamo, PhD, is a research scientist and epidemiologist focused on how nutrition, lifestyle, and environmental factors influence health. An Assistant Professor at the University of Maryland School of Medicine, he has led numerous clinical studies, published widely, and is a trusted advisor and educator in integrative and lifestyle medicine. THANKS TO OUR SPONSOR BetterWay Health (Consumers) BWHLabs (Practitioners) WEBSITE: http://bwhlabs.com/kara EXCLUSIVE OFFER FOR NEW FRONTIERS LISTENERS Book a practitioner call and receive a complimentary bottle of beta-glucan to try personally or with a patient at http://bwhlabs.com/kara CONNECT with DrKF Want more? Join our newsletter here: https://www.drkarafitzgerald.com/news... Or take our pop quiz and test your BioAge! https://www.drkarafitzgerald.com/bioa... Instagram: / drkarafitzgerald Facebook: / drkarafitzgerald DrKF Clinic: Patient consults with DrKF physicians including Younger You Concierge: https://tinyurl.com/yx4fjhkb Younger You Practitioner Training Program: www.drkarafitzgerald.com/trainingyyi/ Younger You book: https://tinyurl.com/mr4d9tym Better Broths and Healing Tonics book: https://tinyurl.com/3644mrfw