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Organic First Approach to Mania | A Structured Clinical Framework for PG Psychiatry Mania is a symptom, not a diagnosis. Before labeling a presentation as primary bipolar disorder, clinicians must systematically rule out organic brain, systemic, and metabolic causes. This educational video presents an *organic first approach to mania*, designed for postgraduate psychiatry trainees. It walks through history-based red flags, examination clues, tiered investigations, and a practical differential diagnosis framework to identify neurological, medical, and systemic causes of manic presentations. What this video covers • Temporal profile and phenomenology of mania • Red flags suggesting organic or neurological etiology • Key physical and neurological examination findings • Tiered investigation strategy for new-onset or atypical mania • VINDICATE framework for differential diagnosis • Autoimmune, infectious, metabolic, endocrine, vascular, degenerative, and drug-induced causes of mania Who should watch • MD and DNB Psychiatry residents • Neurology residents • MBBS interns and senior medical students • Clinical psychologists and mental health professionals This structured approach helps prevent misdiagnosis, delayed identification of organic illness, and inappropriate labeling of secondary mania as primary psychiatric disorder. Keywords: organic mania, secondary mania, approach to mania, PG psychiatry, differential diagnosis of mania, neuropsychiatry, autoimmune encephalitis, psychiatry education, psychiatry residents, clinical psychiatry Get a visual summary of this topic at https://neuropsychddx.neocities.org/i...