Molecular Networking for MetID: Identifying Drug Metabolites with Ometa Flow скачать в хорошем качестве

Molecular Networking for MetID: Identifying Drug Metabolites with Ometa Flow

Understanding how a drug is modified in the human body is crucial for assessing its safety and efficacy. Every new drug candidate must undergo metabolite identification (MetID) studies to determine which metabolites are formed and how they affect the absorption, distribution, metabolism, and excretion (ADME) and pharmacokinetic/pharmcodynamic (PK/PD) parameters of the drug. This video tutorial companion to our MetID application note (https://www.ometalabs.net/application...) highlights how untargeted metabolomics and molecular networking can rapidly identify drug metabolites, even when their potential biotransformations are not known in advance. In this video, you'll learn: The principles of molecular networking in the context of MetID How to use Ometa Flow for analyzing mass spectrometry data How to create custom libraries for target analytes Strategies for identifying and interpreting drug metabolites You can follow along using these tasks: MSMS-Chooser Task: https://showcase.ometalabs.online/sta... Molecular Networking Task: https://showcase.ometalabs.online/sta... Statistics Task: https://showcase.ometalabs.online/sta... About Ometa Flow Ometa Flow is a web-based platform designed for mass spectrometry data analysis, offering tools for molecular networking, statistical analysis, and data visualization. Its user-friendly interface facilitates comprehensive analysis for both novice and experienced researchers. Helpful Links: Learn more about Ometa Labs: https://www.ometalabs.net/ Read the application note: https://www.ometalabs.net/application... Subscribe to our channel for more tutorials and updates on mass spectrometry data analysis. As always, if you have any questions, feel free to contact us at https://www.ometalabs.net/contact.