Serotonin (Purves' Neuroscience, 6/e, Ch 6.10) скачать в хорошем качестве

Serotonin (Purves' Neuroscience, 6/e, Ch 6.10)

I. Introduction to Serotonin Serotonin is a biogenic amine neurotransmitter. It is also known as 5-hydroxytryptamine or 5-HT. It was first thought to increase vascular tone. Neurons in the raphe region produce serotonin. These brainstem neurons project to the forebrain. II. Serotonin Synthesis and Removal Tryptophan is the dietary precursor to serotonin. Tryptophan-5-hydroxylase initiates its synthesis. Vesicular monoamine transporters load it up. Serotonin transporters remove it from the cleft. Monoamine oxidase breaks down excess serotonin. III. Serotonin Receptors in the Brain Most serotonin receptors are metabotropic types. These receptors use G-proteins to alter cells. The 5-HT3 receptor is an ionotropic channel. It forms a nonselective excitatory cation pore. LSD hallucinogens activate metabotropic types. IV. Serotonin Functions and Disorders Serotonin regulates sleep, waking, and mood. It also mediates satiety and lowers food intake. Defects are linked to depression and anxiety. SSRI drugs like Prozac inhibit serotonin uptake. Bipolar disorder and schizophrenia involve 5-HT,. V. Additional Resource Support See NourishED RFI's NotebookLM Resource Support Page. https://notebooklm.google.com/noteboo... VI. Source Source: Purves, D., Augustine, G. J., Fitzpatrick, D., Hall, W. C., LaMantia, A.-S., Mooney, R. D., Platt, M. L., & White, L. E. (Eds.). (2018). Neuroscience (6th ed.). Sinauer Associates. https://www.academia.edu/43014289/Neu... #Serotonin #Neurotransmitters #Neuroscience #MentalHealth #SERT #MAO #ssri #Psychiatry #MedicalEducation #LSD #tryptamines #5htp