Beyond the Genetic Code: A Revolutionary New Perspective on Cancer and its Treatment скачать в хорошем качестве

Beyond the Genetic Code: A Revolutionary New Perspective on Cancer and its Treatment

In this thought-provoking ISB Research Roundtable presentation and Q&A, Dr. Sui Huang challenges the long-held genetic paradigm of cancer, arguing that mutations alone cannot fully explain the disease's complexity and the frequent failure of targeted therapies. He proposes a paradigm shift toward understanding cancer as a disease of cell states and their transitions, driven by non-genetic factors and the inherent plasticity of cells. Dr. Huang draws parallels to complex adaptive systems, highlighting how aggressive attempts to eradicate cancer cells can paradoxically lead to more resilient and malignant forms. The Q&A discussion with Dr. Nitin Baliga explores the implications of this new perspective for designing gentler, non-toxic therapies that aim to reprogram cancer cells and their microenvironment rather than simply killing them.