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Apply to join Foresight Biotech & Health Extension program: https://foresight.org/focus-areas/lon... A group of scientists, entrepreneurs, funders, and institutional allies who cooperate to advance biotechnology to reverse aging and extend human healthspan. This group is sponsored by 100 Plus Capital. http://100pluscap.com/ Kris Borer | Replacement Technology for Radical Life Extension Abstract: Aging is modifiable through small molecules and gene therapies, yet both approaches face significant limitations. Small molecules can reach widespread areas of the body but often have limited efficacy and unintended side effects. Gene therapies, while precise and powerful, currently lack the means for reliable, systemic application in adults. These challenges hinder their potential to substantially extend human lifespan. A promising alternative is the replacement of damaged or diseased tissues and organs with healthy substitutes. This strategy bypasses the complexities of targeting individual aging pathways, as demonstrated in modern transplantation practices: when a liver disease cannot be cured, a new liver can restore health. This seminar explores current replacement therapies, emerging technologies under development, and their potential to revolutionize the treatment of aging and transform medicine in the near future. Bio: Kris Borer is an entrepreneur with a background in robotics and AI. He invests in early-stage companies working on longevity technology and leads the Longevity Biotech Fellowship's replacement working group. He is also the author of a non-fiction book on libertarian ethics. ══════════════════════════════════════ About The Foresight Institute The Foresight Institute is a research organization and non-profit that supports the beneficial development of high-impact technologies. Since our founding in 1986 on a vision of guiding powerful technologies, we have continued to evolve into a many-armed organization that focuses on several fields of science and technology that are too ambitious for legacy institutions to support. From molecular nanotechnology, to brain-computer interfaces, space exploration, cryptocommerce, and AI, Foresight gathers leading minds to advance research and accelerate progress toward flourishing futures. We are entirely funded by your donations. If you enjoy what we do please consider donating through our donation page: https://foresight.org/donate/ Visit https://foresight.org, subscribe to our channel for more videos or join us here: • Twitter: / foresightinst • Facebook: / foresightinst • LinkedIn: / foresight-institute ══════════════════════════════════════ Timecodes 00:00 Introduction and Seminar Overview 00:27 Understanding Radical Life Extension 01:00 Exploring Replacement Technology 01:28 Potential Solutions for Radical Life Extension 02:23 The Role of Bios Stasis 03:02 Technological Timelines and Challenges 06:08 Replacement Technology Roadmap 06:42 Mass Production and Automation in Transplantation 08:50 Current Capabilities and Future Prospects 18:05 Challenges and Innovations in Brain Replacement 22:27 Q&A Session 28:45 Intriguing Questions on Organ Growth 29:24 Concerns About Replacement and Xenotransplantation 30:31 Optimism Around Artificial Wombs 31:31 Radical Body Replacement and Aging Reversal 32:15 Brain and Body Aging Interconnection 35:52 Exploring Brain Replacement and Digital Consciousness 40:18 Robotic Surgery and Replacement Therapies 41:53 Challenges in Rejuvenation and Longevity 45:25 Final Thoughts and Future Prospects