Inhaled Corticosteroids: Pharmacology Made Easy & Clinically Relevant скачать в хорошем качестве

Inhaled Corticosteroids: Pharmacology Made Easy & Clinically Relevant

In this episode, Dr. Busti reviews inhaled corticosteroids (ICS) as essential anti-inflammatory therapy in asthma and some patients with COPD. Inhaled corticosteroids remain the first-line maintenance treatment for persistent asthma, reducing exacerbations, hospitalizations, and mortality. In COPD, their use is selective—mainly in moderate to severe disease with frequent exacerbations and eosinophils ≥100 cells/µL, often in combination with LABA/LAMA therapy. The episode highlights key agents (beclomethasone, budesonide, ciclesonide, fluticasone, mometasone), dose-equivalence ranges, and device technique differences (MDI, DPI, nebulizer). Adverse effects of ICS include dysphonia, oropharyngeal candidiasis, and rare systemic absorption effects such as adrenal suppression or bone loss; proper inhalation technique and mouth rinsing help minimize risks. 👉 Access downloads for this video at https://www.thisiswhy.health/topics/p... 👉 Get more with a free membership at https://www.thisiswhy.health/ Access free downloads from our videos Access deep dive content from Dr. Busti Organize content via playlists & collections Join live Q&A Receive member newsletters Coupons & discounts for exam prep resources 00:00 Introduction to Inhaled Corticosteroids (ICS) 01:07 Why ICS Work in Asthma vs COPD: Pathophysiologic Differences 03:30 ICS Indications: First-Line Asthma Therapy & Select COPD Use 03:49 Mechanism of Action: Airway Inflammation, Edema & Remodeling 07:16 Anatomy Impact on Drug Delivery: Absorption & AEs 14:10 Airway Anatomy Deep Dive: Conducting vs Respiratory Zones 17:05 Steroid Effects on Beta-2 Receptors & Bronchodilator Response 21:00 ICS Dosing: Low, Medium, High Doses Across Age Groups 23:55 Adverse Effects: Thrush, Adrenal Suppression, Bone Density 26:40 Clinical Considerations: Neutrophil vs Eosinophil Inflammation 34:10 Inhaler Technique & Counseling Points: MDI, DPI, Nebulizer 👍 If this helped you, please like, subscribe, and share it with a classmate or colleague. That will help this new channel continue producing free, high-yield medical education content. 🔔 Don’t forget to turn on notifications so you don’t miss upcoming lectures on diuretics, antihypertensives, antibiotics, and more! #InhaledCorticosteroids #AsthmaPharmacology #pharmacology #Pulmonology #medicaleducation Disclaimer: This content is for educational purposes only and is not intended to provide medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider regarding a medical condition.