Renal | Glomerular Filtration скачать в хорошем качестве

Renal | Glomerular Filtration

Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this renal physiology lecture, Professor Zach Murphy breaks down the essential principles of Glomerular Filtration, the first step in urine formation and a critical process in maintaining homeostasis. Building on anatomical context from the nephron and glomerulus, this lecture helps you understand how the kidneys filter plasma and regulate fluid and solute balance at the level of the glomerulus. We begin by revisiting the anatomy of the renal corpuscle, focusing on Bowman’s capsule, the glomerular capillaries, and the specialized filtration membrane composed of fenestrated endothelium, basement membrane, and podocyte slit diaphragms. You’ll learn how this barrier allows the passage of water and small solutes while restricting proteins and cellular elements. The lecture walks through the Starling forces that drive filtration: glomerular capillary hydrostatic pressure, Bowman’s space hydrostatic pressure, and plasma oncotic pressure. We explain how these forces contribute to net filtration pressure and how changes in afferent and efferent arteriole tone modulate glomerular filtration rate (GFR). Clinical correlations are introduced to emphasize the impact of conditions like hypotension, volume depletion, glomerulonephritis, and renal artery stenosis on GFR. The role of inulin and creatinine in measuring GFR is also discussed, reinforcing important diagnostic tools used in both physiology and clinical nephrology. Enjoy the lecture and support us below! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media   / ninjanerdlectures     / ninjanerdlectures     / ninjanerdlectures   https://x.com/ninjanerdsci/   / ninja-nerd   💬 Join Our Community Discord:   / discord   #ninjanerd #GlomerularFiltration #Renal