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Methylene blue was the first synthetic medicine ever created. 140 years later, we're discovering it might be one of the most powerful tools for brain health and longevity. Here's what the research actually shows. Some links are affiliate links so we will earn a commission when they are used to purchase products. I--------------------- If you would like to support our channel please consider joining our Patreon / modernhealthspan Renue By Science (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR BiOptimizers (15% off: Modern10) https://bit.ly/42OqRVW - Magnesium Breakthrough Stemregen (15% off: MODERN) US only https://tinyurl.com/45z968yr Qualia (15% off: MODERN) Senolytic: https://tinyurl.com/22t9thrn • Mind: https://tinyurl.com/5hatj2t2 Life Extension ($10 off $50 order) NAC: https://tinyurl.com/vzvbde99 • Ergothioneine 25mg https://tinyurl.com/48h2bnst NOVOS ($5 off: 5OFFMHS24) https://novos.sjv.io/QyWP7o, https://novos.sjv.io/NOVOS n1o1 (10% off: Modern) https://tidd.ly/3IczGRW - Nitric Oxide Lozenges Wellness Extract (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E AX3 Life (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin Oxford Healthspan (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine Nuchido (20% off first order: MODERN20) https://nuchido.com/MODERN - Time+ --------------------- Dr. Francisco Gonzalez-Lima has spent decades researching methylene blue, the first synthetic medicine in history. In this conversation, he explains how this unique compound enhances mitochondrial function, increases cellular energy production, and reduces oxidative stress; all at very low doses. We discuss the critical importance of dose (low dose benefits, high dose harms), why pharmaceutical-grade purity matters, and how to personalize your dosing using a simple urine test. Dr. Gonzalez-Lima also addresses common misconceptions from failed Alzheimer's trials and explains why those studies used the wrong approach. Looking ahead, he shares his plans to combine methylene blue with near-infrared light therapy and MCT oil for his upcoming clinical trial on mild cognitive impairment. Whether you're interested in cognitive enhancement, neuroprotection, or healthy aging, this is essential viewing. 📚 Chapters 0:00 What is Methylene Blue? History and Chemistry 3:46 The "Magic Bullet" Effect on Nervous Tissue 6:37 Dose-Dependent Effects: Low vs High Dose 10:07 How Methylene Blue Supports Mitochondrial Function 15:35 The Double Action: Energy + Antioxidant Protection 23:08 Why Methylene Blue is Different from Other Antioxidants 30:56 Preclinical Studies: Animal Models and Cognitive Decline 35:40 The Alzheimer's Trials Misconception 40:45 Age-Related Cognitive Decline Studies 45:31 Dosing Guidelines: Finding Your Personal Dose 54:27 Low Dose vs High Dose: The Hormetic Curve 1:00:00 Pharmaceutical Grade vs Chemical Grade Purity 1:07:37 Personalizing Your Dose Using Urine Color 1:15:14 Combining Methylene Blue with Near-Infrared Light 1:20:01 Adding Ketones/MCTs: The Triple Combination 1:25:28 Future Study: Mild Cognitive Impairment Trial 1:31:03 Final Thoughts and Where to Learn More 🌐Links in this video Dr Gonzalez-Lima's page https://liberalarts.utexas.edu/psycho... #methyleneblue #cognitivehealth #mitochondria