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Official Ninja Nerd Website: https://ninjanerd.org Ninja Nerds! In this embryology lecture, Professor Zach Murphy dives into the complex and dynamic development of the vascular system, outlining how the embryonic blood vessels form, remodel, and differentiate into the mature arterial and venous networks. This lecture provides a foundational understanding of how vascular structures arise from mesoderm and undergo intricate transformations to support the growing embryo. We begin by forming blood islands and vasculogenesis, where endothelial precursors organize into primitive vascular tubes. Zach then walks through angiogenesis, the sprouting and remodeling vessels that expand the early circulatory network. Key signaling molecules like VEGF and FGF are discussed in relation to their roles in regulating vascular development. The lecture continues with a detailed breakdown of the aortic arch system, explaining how the six paired aortic arches evolve into major vessels like the aortic arch, subclavian arteries, pulmonary arteries, and ductus arteriosus. You’ll also learn about the development of the cardinal, vitelline, and umbilical veins, which contribute to forming the superior and inferior vena cava, portal system, and other venous structures. Enjoy the lecture and support us below! Table of Contents: 0:00 Lab 0:30 Vasculogenesis 12:47 Development of the Arterial System 34:11 Development of the Venous System 1:03:32 Comment, Like, SUBSCRIBE! 🌐 Official Links Website: https://www.ninjanerd.org Podcast: https://podcast.ninjanerd.org Store: https://merch.ninjanerd.org 📱 Social Media / ninjanerdlectures / ninjanerdlectures / ninjanerdlectures https://x.com/ninjanerdsci/ / ninja-nerd 💬 Join Our Community Discord: / discord #ninjanerd #DevelopmentofVascularSystem #Embryology