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Fix Your Hunger Hormones

• hypothalamus acts as the control center for hunger and satiety • Ghrelin is a hormone that is produced and released mainly by the stomach with small amounts also released by the small intestine, pancreas and brain. • Ghrelin has numerous functions. It is termed the ‘hunger hormone’ because it stimulates appetite, increases food intake and promotes fat storage. When administered to humans, ghrelin increases food intake by up to 30%; it circulates in the bloodstream and acts at the hypothalamus, an area of the brain crucial in the control of appetite. • Fiber will stretch the stomach and let your brain know you are full • Ghrelin goes up after intense dieting explaining why it is difficult to maintain weight loss in some folks • Patients who lose weight after bypass surgery have been found to have lower ghrelin levels than those who lose weight by other means such as diet and exercise, which may partly explain the long-lasting success of this treatment. • Leptin is the opposite: satiety hormone secreted by fat cells • Talks directly to the hypothalamus • Keep inflammatory foods away which will store and create fat cells • Exercise!!!!! Increase leptin • GLP-1 is normally released from your small intestine when you eat, and works to slow down the process by which food leaves your stomach, controlling your blood sugar after meals. • Makes you feel ful GLP-1 decreases acid secretion and decreases gastric emptying l • • GLP-1 increases sugar usage in the muscle • • The benefit of GLP-1 agonists Used in some diabetic meds like Byetta, trulicity, victoza is that they mimic GLP-1 hormone • Inflammation lowers this so it make us feel continuously hungry!! • Insulin we all know as a regulator for sugar and it helps with storage and unfortunately will not allow fat to break down. STOP CARBS • CCK Produced in the duodenum and tells us we are full and fat consumption will trigger this • Fat releases CCY (and we use this tactic to diagnose GB problems)to get the GB and pancreas working to digest and • Fiber and protein help make more CCY • PYY (Peptide YY) will reduce an appetite • Insulin in response to a carbohydrate is designed to bring sugar into the cell for energy, but high spike in insulin will sitmulate appetite • Cortisol from the adrenal (think of the word adrenaline) gland at times of stress will lead to over eating as there is a cascade of events where it will stimulate insulin production, increasing hunger • Dopamine, nueorchemical , if it is low, yield hunger pangs • Coffee increases dopamine (suppressing appetite for a time being) • Fasting • Cannabis lowers dopamine and give you intense munchies!! • Dopamine made using L-tyrosine, so eat :fava beans, chicken, oats, mustard greens, ricotta, chocolate, edamame • Estrogen curbs appetite like leptin • Progesterone can increase appetite and Megace, which is synthetic progestin treats appetite in HIV patients • T can increase ghrelin, increasing appetite