The iCELLis™ bioreactor: Pioneers of gene therapy скачать в хорошем качестве

The iCELLis™ bioreactor: Pioneers of gene therapy

Spinal muscular atrophy (SMA) is a devastating genetic disease that progresses rapidly, often leading to death in infancy. This video explores how a gene therapy manufacturer, in collaboration with Cytiva, achieved FDA approval for a groundbreaking treatment using the iCELLis™ bioreactor. Designed to accelerate time to market for adherent cell culture, the iCELLis bioreactor has become a cornerstone of innovation in the production of viral vectors for gene therapy. At the heart of this success was a shared determination to bring life-saving therapies to children in need. Cytiva's swift action and expertise in industrializing the solution played a critical role in overcoming the challenges of manufacturing these complex biologics. The bioreactor's single-use design not only enables faster production but also supports scalability and flexibility in biologics development. iCELLis™ bioreactors are widely used across multiple therapeutic applications, including the production of viral vaccines, oncolytic vaccines, and viral vectors essential for gene therapy. Its advanced technology supports high-yield adherent cell culture, making it a preferred choice for developers seeking reliable and efficient manufacturing solutions. Gene therapy relies on viral vectors to deliver genetic material into cells, offering the potential to treat and even cure genetic disorders. The iCELLis bioreactor has proven instrumental in this field, enabling the production of high-quality viral vectors to meet stringent regulatory requirements. Its single-use format ensures sterility and simplifies processes, providing a robust platform for innovative therapies. The commitment from Cytiva to advancing biopharma technologies continues to support breakthroughs in gene therapy, helping manufacturers bring novel treatments to market faster. This pioneering spirit is paving the way for transformative therapies that can change lives. Learn about the people and technologies behind the innovations: https://www.cytivalifesciences.com/en... Explore our solutions for gene therapy: https://www.cytiva.com/genetherapy By leveraging advanced solutions like the iCELLis bioreactor, Cytiva is empowering gene therapy manufacturers to deliver hope to patients worldwide. Chapters 00:00:00 The power of long-term collaboration in therapy 00:00:35 Viral vaccine production with the iCELLis bioreactor 00:00:59 From prototype to industrialized bioreactor 00:01:26 Developing prototypes into industrial bioreactors 00:01:59 Innovations in software-consumable hardware 00:02:30 Urgent development of life-saving technology 00:02:55 Innovations in space-efficient vaccine production 00:03:20 Understanding the iCellis bioreactor: viral DNA therapy 00:03:52 SMA treatment: a breakthrough in genetic disease therapy 00:04:30 Baby Pia and the impact of SMA treatment in Belgium 00:04:55 Customer collaboration in Isers development 00:05:17 The motivation behind life-changing pharmaceutical innovations 00:05:50 Customer-centric product development #bioreactor #viralvectors #genetherapy #biopharma