Cell line development and AAV: Pioneers of gene therapy скачать в хорошем качестве

Cell line development and AAV: Pioneers of gene therapy

Viral vector-based gene therapies, like AAV gene therapy, are transforming medicine by providing new hope for treating rare genetic diseases and common conditions alike. This video explores how our expertise in cell line development is driving innovation in AAV production, making gene therapies more scalable, cost-effective, and accessible to patients. What we cover in this video on AAV production: • The critical role of stable, inducible producer cell lines in scalable AAV production. • How an in-depth understanding of viral vector biology and manufacturing has enabled significant advances in cell line development. • Insights into how these breakthroughs are reducing production costs and helping make AAV gene therapy more widely available. Our pioneering work in cell line development and AAV production is setting new standards for efficiency and reliability, enabling researchers to deliver on the promise of advanced therapies. By leveraging cutting-edge solutions, we’re helping address both rare and complex diseases, giving patients new hope for a cure. Explore more stories of biopharma innovation: https://www.cytivalifesciences.com/en... Learn more about cell line development and AAV production: https://www.cytivalifesciences.com/en... Discover how Cytiva is paving the way for next-generation gene therapies with groundbreaking advances in cell line development and AAV production. Episode features commentary from Tobias Bonifert, Dovilé Woods, and Michelle Hussong Chapters: 00:00:00 Revolutionary gene therapy: from terminal illness to cure 00:00:42 Early challenges in gene therapy 00:01:06 Gene therapy breakthroughs with AAV 00:01:34 Importance of cell line in viral vector manufacturing 00:02:04 History and expertise in cell line development 00:02:33 Challenges in scaling monoclonal antibodies for clinical trials 00:03:00 Skepticism and stable producer cells 00:03:23 Integrating AAV in a cell: the pioneering method 00:03:51 Innovations in gene editing and cell development techniques 00:04:22 Importance of stable cell lines in gene therapy manufacturing 00:04:50 How gene therapies are transforming lives 00:05:16 Understanding virus infection mechanisms 00:05:49 The impact of genetic cures on patients #genetherapy #biopharma #lifesciences #cytiva