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📢 Ask Dr. Bikman’s Digital Mind: https://benbikman.com/ben-bikmans-dig... 📢 Dr. Bikman’s Community & Coaching Site, Insulin IQ: https://insuliniq.com 📢 Become an Insider, Ben’s website: https://www.benbikman.com In this important Metabolic Classroom lecture, Dr. Bikman examines the use of statins in women, particularly for primary prevention of cardiovascular disease. While statins are widely prescribed to lower LDL cholesterol and ApoB levels, Ben highlights research showing that these markers are weak predictors of cardiovascular risk in women. In contrast, metabolic markers like insulin resistance and type 2 diabetes are far more predictive—often increasing cardiovascular risk by up to 10-fold. He discusses how statins may ironically worsen metabolic health by impairing insulin sensitivity, increasing type 2 diabetes risk (especially in postmenopausal women), and altering the gut microbiome in a way that reduces GLP-1 production. He also notes statin-induced side effects that disproportionately affect women, such as muscle pain, brain fog, and even potential risks during pregnancy. While statins may have limited value for secondary prevention, their risks—especially in women who haven’t had a cardiovascular event—warrant serious caution. In the final portion of the lecture, Dr. Bikman outlines practical, lifestyle-based strategies to improve metabolic health without the need for statins. These include resistance training, a smart-carb diet, and stress/sleep management. He also shares evidence-based supplements like CoQ10, omega-3s, magnesium, and alpha-lipoic acid that may help mitigate some of statins’ side effects if they are used. Show Notes/References: For complete show notes and references, we invite you to become an Insider subscriber. You’ll enjoy real-time, livestream Metabolic Classroom access which includes live Q&A with Ben after the lecture, ad-free podcast episodes, show notes and references, and online, live Office Hours access with Dr Bikman. It also includes Ben’s Research Review Podcast, and a searchable archive that includes all Metabolic Classroom episodes and Research Reviews. Learn more: https://www.benbikman.com Translation Notes: You can click the gear icon at the bottom of this video to auto-translate captions. For example, to translate into Polish, select Subtitles, choose Auto-Translate, then first choose English, then choose Auto-Translate again, then choose Polish.) In addition, our channel has first access to YouTube’s new, innovative “auto-dubbing” feature. The process currently supports translations from English into many languages, with more to come. Click on the gear icon, then choose “Audio track” to access. (Sometimes this availability is delayed, so check back often.) Timestamps (approximate): 00:01 – What Are Statins and How Do They Work? 01:56 – LDL Cholesterol and the Dogmatic View 02:50 – Primary Prevention in Women 05:00 – Meta-Analyses and Risk Reduction 06:09 – LDL vs. ApoB vs. CRP 08:25 – Metabolic Health Predictors Are Stronger 10:39 – Framingham Study Confirms Insulin Resistance 11:44 – The Irony of Statin Use 12:44 – Statins Increase Type 2 Diabetes Risk in Women 13:43 – Statins Lower GLP-1 via Microbiome Changes 14:48 – CoQ10 and Mitochondrial Function 15:57 – Muscle Side Effects in Women 17:05 – Cognitive and Mental Health Risks 18:08 – Hormonal Changes and Menopause 19:08 – Pregnancy and Statins 20:24 – Summary: Weak Lipid Markers vs. Strong Metabolic Markers 21:25 – Evidence-Based Supplement Support 22:19 – Final Thoughts and Cautions #Statins #WomensHealth #InsulinResistance #MetabolicHealth #LDLCholesterol #ApoB #Type2Diabetes #GLP1 #CoQ10 #CholesterolMyths #StatinRisks #HormonesAndHealth #MenopauseHealth #CardiovascularRisk #DiabetesPrevention #StatinsSideEffects #BrainFog #MusclePain #StatinsAndPregnancy #BetterHealth Ben’s favorite yerba mate: https://ufeelgreat.com/usa/en/c/1BA884 Ben’s favorite meal-replacement shake: https://gethlth.com (discount: BEN10) Ben’s favorite allulose source: https://rxsugar.com (discount: BEN20) Ben’s favorite health check-up for men: https://blokes.co/drben15 (discount: DRBEN15)