Tetrahydrobiopterin BH4 and dihydrobiopterin BH2 cofactors involved in various biochemical processes скачать в хорошем качестве

Tetrahydrobiopterin BH4 and dihydrobiopterin BH2 cofactors involved in various biochemical processes

Tetrahydrobiopterin (BH4) and dihydrobiopterin (BH2) are important cofactors involved in enzymatic reactions, particularly in the metabolism of amino acids and neurotransmitters. Tetrahydrobiopterin (BH4) Function: BH4 is a cofactor for enzymes that synthesize dopamine, serotonin, norepinephrine, and nitric oxide. Role in Health: Supports neurological function, cardiovascular health, and immune response. Deficiency Risks: Low BH4 levels are linked to phenylketonuria (PKU), depression, and cardiovascular diseases. Dihydrobiopterin (BH2) Function: BH2 is an oxidized form of BH4, which must be converted back to BH4 for proper enzymatic function. Conversion Process: The enzyme dihydropteridine reductase (DHPR) regenerates BH4 from BH2. Imbalance Risks: Excess BH2 can lead to oxidative stress and impaired neurotransmitter synthesis. Clinical Importance BH4 supplementation is used in PKU treatment and neurological disorders. Maintaining optimal BH4/BH2 balance is crucial for mental health and cardiovascular function. #Tetrahydrobiopterin #dihydrobiopterin