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Presented December 6, 2025 by Kuakini Health System in cooperation with Kuakini Auxiliary and Japanese Women's Society Foundation at Hale Pulama Mau, Kuakini Health System. www.kuakini.org 00:00 Open - Gregg Oishi, President and CEO, Kuakini Health System 00:50 Dr. Kamal Masaki, M.D. 01:16 Alzheimer's Disease is a Public Health Crisis 04:01 Healthy Brain Aging 06:52 Maintaining Brain Health 12:41 What is Dementia? 18:14 Mild Cognitive Impairment (MCI) 23:16 Sub-Types of Dementia 27:48 Kuakini Honolulu Heart Program & Honolulu-Asia Aging Study 32:29 Early Detection is Important 38:06 Symptoms & Diagnosis 44:49 Alzheimer's Disease 54:22 Treatment 1:03:04 Safety Issue in Dementia 1:05:19 Summary of Treatment Strategies 1:06:25 Dementia Goals of Care 1:07:55 Acknowledgments 1:08:29 Q&A Have there been any studies for Japanese-American women? 1:10:05 Q&A re: The Nun Study 1:12:27 Q&A Do you have genetic testing for dementia? 1:13:12 Q&A Is there a distinction between Japanese men born in Japan and USA? 1:15:11 Q&A How do you help those with hearing or vision impairments? 1:16:31 Q&A What can a blood test show for dementia or Alzheimer's? 1:18:26 Q&A Are there any medications for Mild Cognitive Impairment (MCI)? 1:19:42 Q&A Is there any association between soy consumption and dementia? 1:21:09 Q&A Are brain games beneficial and what types are more beneficial? 1:22:08 Q&A Can you comment of the Okinawan diet? 1:22:50 Q&A What do you think of watching TV, like National Geographic or History Channel? 1:23:43 Q&A What effect do artificial sweeteners have on dementia? 1:24:48 Q&A Comment on statin use. 1:26:20 Q&A Comment of red light therapy. 1:26:45 Close - Volunteer opportunities at Kuakini • Learn about brain aging, and what you can do to keep your brain as healthy as possible • Understand types of dementia, risk factors, and the importance of early detection • Know about symptoms, prevention, currently available treatment strategies and community resources GUEST SPEAKER: Kamal Masaki, M.D. Director of Research Kuakini Medical Center Professor and Chair of the Department of Geriatric Medicine John A. Burns School of Medicine, University of Hawaii Director of the John A. Hartford Foundation Center of Excellence in Geriatrics University of Hawaii Principal Investigator and Clinical Director KuakiniHonolulu Heart Program and Kuakini Honolulu-Asia Aging Study Co-Principal Investigator Pacific Islands Geriatrics Workforce Enhancement Program Kuakini Health System Marketing and Public Relations 347 N. Kuakini St. Honolulu, HI 96817 [email protected] 808-547-9168