Why Exogenous Ketones Are the Metabolic Game Changer | Dr Eric Plaisance скачать в хорошем качестве

Why Exogenous Ketones Are the Metabolic Game Changer | Dr Eric Plaisance

Dr. Eric Plaisance explains how exogenous ketones may provide fasting benefits without dietary restriction - the hormetic effects of mimicking starvation while fed. Plus: ketone salts vs esters, his personal protocol, and why performance claims don't hold up. If you would like to support our channel please consider joining our Patreon   / modernhealthspan   ~~~~~~~~~~~~~~ Qitone (10% off: HEALTH10) https://tidd.ly/4jGklry Qitone Esters Powder Renue By Science (10% off: MHS) https://tinyurl.com/bdew4bfs NMN Powder • Lipo NR BiOptimizers (15% off: MHBIO) https://bit.ly/47VAa8f - Magnesium Breakthrough Stemregen (15% off: MODERN) US only https://tinyurl.com/45z968yr Wellness Extract (10% off: MODERNWE) http://wellnessextract.com/RICHARDWE Geranylgeraniol • Vit E AX3 Life (20% off: MODERN20) https://tinyurl.com/2t3w26nw - Astaxanthin Oxford Healthspan (15% off: MHS) https://tinyurl.com/hrxfnzpn - Spermidine Seeking Health (10% off: Richard10) https://crrnt.app/SEEK/-dm0MyrQ, Histamine Nutrients https://crrnt.app/SEEK/EpM7paAO ProHealth* (15% off: MODERN) https://prohealth.pxf.io/aObQRR NMNH 500mg These are affiliate links - using them supports the channel at no extra cost to you. ~~~~~~~~~~~~~~ Dr. Eric Plaisance, Associate Professor at University of Alabama Birmingham, has spent over a decade studying exogenous ketone esters. His most intriguing finding? Ketones may allow us to "mimic a starvation environment when we're not starving" - potentially triggering the same hormetic benefits as fasting without dietary restriction. In this conversation, we explore the anti-inflammatory effects of ketones, the promising research in liver health and cancer, and the practical differences between ketone salts, esters, and MCT oil. Dr. Plaisance shares his personal ketone protocol (including why he takes them before workouts during time-restricted eating), optimal dosing strategies, and why the athletic performance marketing claims don't match the research. We also discuss who should actually consider ketone supplementation versus who should save their money. A grounded, evidence-based perspective on one of longevity's most debated supplements. 📚 Chapters 00:00 Why Ketones Matter Beyond Keto Diets & Fasting 03:47 Ketones as Fuel vs. Fatty Acids – Tissue Differences & Glucose Sparing 06:16 Ketones as Signaling Molecules – Mimicking Aspects of a Ketogenic Diet? 10:01 Differences Between Exogenous Ketones & Long-Term Ketogenic Diet Effects 12:40 How Ketone Production Changes With Aging & Metabolic Dysfunction 15:57 Do We Always Produce Some Ketones – Even After Meals? 17:02 Who Might Benefit Most from Exogenous Ketones? (Inflammation, Cancer, Brain, Heart, Liver) 20:49 Potential in Cancer Models (Preliminary Animal Data) 21:52 Fatty Liver Disease – Surprising Benefits of Exogenous Ketones 23:39 Mechanisms: How Ketones Reduce Liver Fat (Inflammation, Oxidation, etc.) 28:01 Effects on Blood Lipids (Triglycerides, Cholesterol) 29:35 Alzheimer's, Brain Glucose Metabolism & the "Type 3 Diabetes" Concept 32:13 Ketones for Traumatic Brain Injury (TBI) & Concussion Recovery 35:12 Anti-Inflammatory Effects in the Brain – Ongoing Research 36:47 Why Has Ketone Research Been Relatively Slow? (Misconceptions & History) 40:17 Types of Exogenous Ketones: MCTs vs Ketone Salts vs Ketone Esters 44:54 Comparing Different Ketone Esters – Rapid vs Sustained Elevation 45:37 Tolerability & Side Effects – Salts vs Esters 50:11 How Quickly Do Ketones Rise? Duration & Peak Levels 52:52 Best Ways to Measure Ketones (Blood, Urine, Breath) 55:04 What Ketone Level Is Therapeutically Meaningful? 57:53 Typical Doses Used in Human Studies (12–25g) 1:00:29 Do Exogenous Ketones Improve Athletic Performance? (Current Evidence) 1:02:44 Practical Advice: When, How & How Much to Take Ketones 1:06:12 Dr. Plaisance's Personal Reasons for Taking Ketone Esters 1:09:44 Which Ketone Claims Are Solid vs. Overhyped? (Honest Assessment) 1:13:03 Closing & Where to Follow Dr. Eric Plaisance's Research 🌐Links in this video Dr Plaisance's page at Alabama University https://scholars.uab.edu/2392-eric-pl... #ketones #ketogenicdiet #longevity